The Josephin-1 Polyclonal Antibody (CAB10426) is a valuable tool for researchers studying Josephin-1, a key player in protein degradation pathways and neurodegenerative diseases. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blotting. By specifically binding to Josephin-1, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in neurobiology and neurodegenerative disorders.Josephin-1 is known for its role in regulating protein clearance through the ubiquitin-proteasome system, making it a crucial factor in maintaining cellular health and function.
Dysregulation of Josephin-1 has been associated with neurodegenerative conditions such as Parkinson's and Alzheimer's diseases, highlighting its importance in understanding and potentially treating these debilitating disorders. The Josephin-1 Polyclonal Antibody offers researchers a powerful tool for unraveling the mechanisms of protein degradation and exploring novel therapeutic interventions in neurodegenerative pathology.
Product Name:
JOSD1 Rabbit Polyclonal Antibody
SKU:
CAB10426
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human JOSD1 (NP_055691.1).
Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Located in membrane.
Purification Method:
Affinity purification
Gene ID:
9929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using JOSD1 antibody (CAB10426) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
