JNK3 Polyclonal Antibody (CAB17408)
- SKU:
- CAB17408
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | JNK3 Polyclonal Antibody |
SKU: | CAB17408 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human JNK3 (NP_620448.1). |
Sequence: | NRPK YAGL TFPK LFPD SLFP ADSE HNKL KASQ ARDL LSKM LVID PAKR ISVD DALQ HPYI NVWY DPAE VEAP PPQI YDKQ LDER EHTI EEWK ELIY KEVM N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK |
Positive Sample: | mouse testis,rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lipid-anchor, Membrane, Mitochondrion, Nucleus. |
Calculated MW: | 44kDa |
Observed MW: | 52kDa |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Purification Method: | Affinity purification |
Gene ID: | 5602 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |