JNK3 Monoclonal Antibody (CAB19075)
- SKU:
- CAB19075
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | JNK3 Monoclonal Antibody |
SKU: | CAB19075 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MAPK10 (P53779). |
Sequence: | VDDA LQHP YINV WYDP AEVE APPP QIYD KQLD EREH TIEE WKEL IYKE VMNS EEKT KNGV VKGQ PSPS GAAV NSSE SLPP SSSV NDIS SMST DQTL ASDT D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK |
Positive Sample: | MCF7,Mouse brain,Mouse testis,Rat brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lipid-anchor, Membrane, Mitochondrion, Nucleus. |
Calculated MW: | 44kDa |
Observed MW: | 53kDa |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Purification Method: | Affinity purification |
Gene ID: | 5602 |
Clone Number: | ARC0366 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |