The JMJD4 Polyclonal Antibody (CAB7992) is specifically designed for research involving JMJD4, a member of the Jumonji domain-containing protein family, known for its involvement in epigenetic regulation and chromatin remodeling. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the JMJD4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in the fields of epigenetics, gene regulation, and developmental biology.
JMJD4 is a key player in regulating gene expression through histone demethylation, influencing processes such as cell differentiation, proliferation, and development. Its role in epigenetic regulation makes it a target of interest in research related to diseases such as cancer, neurodevelopmental disorders, and metabolic conditions. Understanding the function and mechanisms of JMJD4 is crucial for unraveling its therapeutic potential in various disease contexts.
Product Name:
JMJD4 Rabbit Polyclonal Antibody
SKU:
CAB7992
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-463 of human JMJD4 (NP_075383.2).
Enables 2-oxoglutarate-dependent dioxygenase activity. Involved in positive regulation of translational termination and protein hydroxylation. Located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
65094
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using JMJD4 antibody (CAB7992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
