JARID2 Rabbit Monoclonal Antibody (CAB9614)
- SKU:
- CAB9614
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | JARID2 Rabbit Monoclonal Antibody |
SKU: | CAB9614 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human JARID2 (Q92833). |
Sequence: | FEEG PSRK RPRL QAQR KFAQ SQPN SPST TPVK IVEP LLPP PATQ ISDL SKRK PKTE DFLT FLCL RGSP ALPN SMVY FGSS QDEE EVEE EDDE TEDV KTAT N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | JMJ; DIDDF; JARID2 |
Positive Sample: | HT-29,Jurkat,Mouse lung,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 139kDa |
Observed MW: | 150kDa |
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.
Purification Method: | Affinity purification |
Gene ID: | 3720 |
Clone Number: | ARC1658 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |