Based on the information provided in the URL, the JAM2 Polyclonal Antibody (CAB9978) is a valuable tool for research involving JAM2, a protein involved in cell adhesion and immune cell migration. This antibody, produced through the immunization of rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.JAM2, also known as Junctional Adhesion Molecule 2, plays a crucial role in regulating the movement of immune cells within tissues and facilitating their interactions with other cells. By binding specifically to JAM2, this polyclonal antibody enables the detection and analysis of this protein in various cell types, providing insight into its function in immune responses and inflammatory processes.
Research utilizing the JAM2 Polyclonal Antibody can contribute to a better understanding of immune cell trafficking, inflammation, and the development of strategies for targeting JAM2 in diseases such as cancer, inflammation, and autoimmune disorders. By studying the role of JAM2 in these contexts, researchers can potentially uncover new therapeutic targets and treatment approaches for a range of conditions.
Product Name:
JAM2 Rabbit Polyclonal Antibody
SKU:
CAB9978
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-238 of human JAM2 (NP_067042.1).
Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction.
Calculated MW:
33kDa
Observed MW:
36kDa
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
58494
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using JAM2 Rabbit pAb (CAB9978) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
