JAM2 Monoclonal Antibody [PAT21D7AT] (CPAB0695)
- SKU:
- CPAB0695
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT21D7AT
- Applications:
- WB
- ELISA
Description
JAM2 Monoclonal Antibody [PAT21D7AT] (CPAB0695)
The JAM2 Polyclonal Antibody (CPAB0695) is a valuable tool for research involving JAM2, a cell adhesion molecule known for its role in immune cell migration and inflammation regulation. This antibody, developed in rabbits, has high specificity for JAM2 in human samples and is optimized for Western blot applications. By targeting the JAM2 protein, researchers can effectively detect and study this molecule in various cell types, making it an ideal choice for studies in immunology and inflammatory diseases.JAM2, also known as Junctional Adhesion Molecule 2, is a key player in the immune response, particularly in the regulation of leukocyte trafficking and adhesion.
Its involvement in inflammation and immune cell communication positions it as a potential therapeutic target for conditions such as autoimmune diseases and inflammatory disorders. By investigating the function of JAM2, researchers can gain insights into the mechanisms underlying immune responses and potentially develop novel treatment strategies for these diseases.
Product Name: | JAM2 antibody |
Product Sku: | CPAB0695 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human JAM2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human JAM2 protein 21-238 amino acids purified from Ecoli. |
Clone: | PAT21D7AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | JAM2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | Junctional Adhesion Molecule 2 (JAM2) is a member of the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein which is localized at the tight junctions of both epithelial and endothelial cells. JAM2 functions as an adhesive ligand for interacting with various immune cell types, and may have a role in lymphocyte homing to secondary lymphoid organs. |
Synonyms: | Junctional adhesion molecule B, JAM-B, Junctional adhesion molecule 2, JAM-2, Vascular endothelial junction-associated molecule, VE-JAM, CD322. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |