null

JAK2 Monoclonal Antibody [PAT53B7AT] (CPAB0240)

SKU:
CPAB0240
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT53B7AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

JAK2 Monoclonal Antibody [PAT53B7AT] (CPAB0240)

The JAK2 Polyclonal Antibody (CPAB0240) is a valuable tool for researchers studying the Janus kinase 2 (JAK2) protein, a critical player in the JAK-STAT signaling pathway. This antibody, derived from rabbit serum, exhibits high specificity and reactivity towards human samples, making it ideal for Western blot applications. By targeting the JAK2 protein, this antibody enables accurate detection and analysis in a variety of cell types, facilitating research in oncology, hematopoiesis, and immune regulation.JAK2, a tyrosine kinase involved in important cellular processes such as proliferation and differentiation, is commonly dysregulated in various cancers and hematological disorders.

By understanding the role of JAK2 in disease development and progression, researchers can identify potential therapeutic targets and biomarkers for improved diagnosis and treatment. The JAK2 Polyclonal Antibody serves as a valuable tool in unraveling the complex mechanisms involving JAK2, paving the way for advancements in precision medicine and personalized therapy approaches.

Product Name:JAK2 Antibody
Product Sku:CPAB0240
Size:5μg
Host Species:Mouse
Immunogen:Anti-human JAK2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human JAK2 amino acids 114-1132 purified from Ecoli.
Clone:PAT53B7AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:JAK2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Janus Kinase 2 (JAK2) is a protein tyrosine kinase which takes part in a specific subset of cytokine receptor signaling pathways such as cell growth, development, differentiation or histone modifications. JAK2 is linked with the prolactin receptor and is necessary for responses to gamma interferon. Mice which do not express an active protein for JAK2 show embryonic lethality associated with the absence of definitive erythropoiesis.
Synonyms:Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2, JAK2, Janus kinase 2 (a protein tyrosine kinase), JTK10.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products