JAG1 Rabbit Polyclonal Antibody (CAB12754)
- SKU:
- CAB12754
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | JAG1 Rabbit Polyclonal Antibody |
SKU: | CAB12754 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 34-180 of human JAG1 (NP_000205.1). |
Sequence: | QFEL EILS MQNV NGEL QNGN CCGG ARNP GDRK CTRD ECDT YFKV CLKE YQSR VTAG GPCS FGSG STPV IGGN TFNL KASR GNDR NRIV LPFS FAWP RSYT LLVE AWDS SNDT VQPD SIIE KASH SGMI NPSR QWQT LKQN TGVA HFE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AGS; AHD; AWS; HJ1; AGS1; DCHE; CD339; JAGL1; CMT2HH; JAG1 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 134kDa |
Observed MW: | 180kDa |
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Purification Method: | Affinity purification |
Gene ID: | 182 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |