The Izumo4 Polyclonal Antibody (PACO35830) is a crucial tool for researchers studying Izumo4, a protein essential for sperm-egg fusion during fertilization. This antibody, generated in rabbits, is highly specific to Izumo4 in human samples and is validated for use in various applications, including Western blot and immunofluorescence.Izumo4 is a vital player in the process of fertilization, as it is responsible for mediating the fusion of sperm and egg membranes. By targeting Izumo4, researchers can gain insights into the mechanisms underlying fertilization and potentially develop new strategies for contraception or infertility treatments.
This antibody offers researchers a reliable tool for detecting and studying Izumo4 in different cell types and tissues, making it an invaluable resource for reproductive biology and assisted reproductive technology research. Its high specificity and sensitivity make it an ideal choice for scientists interested in unraveling the mysteries of fertilization and reproductive health.
Western blot. All lanes: IZUMO4 antibody at 2µg/ml + Rat gonadal tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 27, 25, 18, 19 kDa. Observed band size: 27 kDa.
Immunofluorescent analysis of HepG2 cells using PACO35830 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO35830 at dilution of 1:100.
Synonyms:
Izumo sperm-egg fusion protein 4 (Sperm 22 kDa protein c113), IZUMO4, C19orf36
UniProt Protein Function:
IZUMO4: Belongs to the Izumo family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 19p13.3Cellular Component: nucleus
