IVD Polyclonal Antibody (CAB23595)
- SKU:
- CAB23595
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Description
| Product Name: | IVD Polyclonal Antibody |
| SKU: | CAB23595 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Mouse,Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-160 of human IVD(NP_002216.3). |
| Sequence: | HSLL PVDD AING LSEE QRQL RQTM AKFL QEHL APKA QEID RSNE FKNL REFW KQLG NLGV LGIT APVQ YGGS GLGY LEHV LVME EISR ASGA VGLS YGAH SNLC INQL VRNG NEAQ KEKY LPKL ISGE |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:2000 - 1:7000 |
| Synonyms: | IVDH; ACAD2; IVD |
| Positive Sample: | Mouse heart |
| Conjugate: | Unconjugated |
| Cellular Localization: | Mitochondrion matrix. |
| Calculated MW: | 47kDa |
| Observed MW: | 42kDa |
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 3712 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from Mouse heart, using IVD Rabbit pAb (CAB23595) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s. |
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