The ITSN2 Polyclonal Antibody (CAB16525) is a valuable tool for researchers studying ITSN2, a protein involved in cellular signaling pathways and endocytosis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ITSN2 protein, this antibody allows for the detection and analysis of ITSN2 in a variety of cell types, making it ideal for research in cell biology, neuroscience, and cancer biology.ITSN2 is known to play a crucial role in controlling cell proliferation, migration, and differentiation, making it a key player in multiple cellular processes.
Its involvement in endocytosis and intracellular signaling pathways has led to interest in studying its function in various diseases, including cancer and neurodegenerative disorders. By understanding the role of ITSN2 in these contexts, researchers can gain valuable insights into potential therapeutic targets for these conditions.
Product Name:
ITSN2 Rabbit Polyclonal Antibody
SKU:
CAB16525
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-620 of human ITSN2 (NP_006268.2).
This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis.
Purification Method:
Affinity purification
Gene ID:
50618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITSN2 Rabbit pAb (CAB16525) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
