The ITPRIP Polyclonal Antibody (CAB11725) is a valuable tool for researchers studying ITPRIP, a protein involved in cellular calcium signaling and apoptosis regulation. This antibody, generated in rabbits, has high specificity for human samples and is suitable for use in Western blot applications. By binding to the ITPRIP protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies in cell biology and cancer research.ITPRIP, also known as inositol 1,4,5-trisphosphate receptor-interacting protein, plays a crucial role in mediating calcium release from intracellular stores and regulating cell survival pathways.
Its involvement in these fundamental cellular processes makes it a promising target for investigating diseases such as cancer, neurodegenerative disorders, and cardiovascular conditions. Understanding the function of ITPRIP is essential for developing new therapies that target calcium signaling pathways and apoptosis mechanisms implicated in these diseases.
Product Name:
ITPRIP Rabbit Polyclonal Antibody
SKU:
CAB11725
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 101-290 of human ITPRIP (NP_203755.1).
This gene encodes a membrane-associated protein that binds the inositol 1,4,5-trisphosphate receptor (ITPR). The encoded protein enhances the sensitivity of ITPR to intracellular calcium signaling. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
85450
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITPRIP Rabbit pAb (CAB11725) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
