ITPR3 Rabbit Polyclonal Antibody (CAB12794)
- SKU:
- CAB12794
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ITPR3 Rabbit Polyclonal Antibody |
SKU: | CAB12794 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 (NP_002215.2). |
Sequence: | EGSE AYQR CESG GFLS KLIQ HTKD LMES EEKL CIKV LRTL QQML LKKT KYGD RGNQ LRKM LLQN YLQN RKST SRGD LPDP IGTG LDPD WSAI AATQ CRLD KEGA TKLV CDLI TSTK NEKI FQES IGLA IHLL DGGN TEIQ KSFH NLMM SDKK SERF FKVL HDRM KRAQ QETK STVA VNMN DLGS QPHE DREP VDPT TKGR VASF SIPG SSSR YSLG PSLR RGHE VSER VQSS EMGT SVLI M |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | IP3R; CMT1J; IP3R3; ITPR3 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 304kDa |
Observed MW: | 304kDa |
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
Purification Method: | Affinity purification |
Gene ID: | 3710 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |