The ITPKB Polyclonal Antibody (CAB3929) is a vital tool for research involving ITPKB, a protein involved in regulating immune responses and inflammatory processes. This antibody, generated in rabbits, is highly specific for detecting ITPKB in human samples and is validated for use in Western blot applications. By binding to the ITPKB protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology, inflammation, and cancer research.ITPKB, also known as inositol-trisphosphate 3-kinase B, plays a crucial role in immune signaling pathways and cellular functions related to inflammation.
Its involvement in these processes makes ITPKB a potential target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of ITPKB is essential for developing targeted therapies that modulate immune responses and inflammatory signaling in these disease contexts.The ITPKB Polyclonal Antibody (CAB3929) offers researchers a reliable tool for investigating the role of ITPKB in various biological processes and disease states, ultimately contributing to advancements in the field of immunology and beyond.
Product Name:
ITPKB Rabbit Polyclonal Antibody
SKU:
CAB3929
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ITPKB (NP_002212.3).
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Purification Method:
Affinity purification
Gene ID:
3707
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ITPKB antibody (CAB3929) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
