The ITIH3 Polyclonal Antibody (CAB9459) is a valuable tool for researchers studying the ITIH3 protein, a member of the inter-alpha-trypsin inhibitor (ITI) family involved in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ITIH3 protein, this antibody enables researchers to detect and analyze ITIH3 expression in different cell types, making it a versatile tool for studies in biochemistry and molecular biology.
ITIH3 is known to play a role in extracellular matrix stabilization and regulation of inflammatory responses, making it a promising target for research into conditions such as cancer, arthritis, and cardiovascular diseases. Understanding the functions of ITIH3 can provide insights into disease mechanisms and pave the way for the development of novel therapeutic interventions that target this protein. Researchers can leverage the ITIH3 Polyclonal Antibody to deepen their understanding of ITIH3 biology and its implications for human health.
Product Name:
ITIH3 Rabbit Polyclonal Antibody
SKU:
CAB9459
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human ITIH3 (NP_002208.3).
This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. Polymorphisms of this gene may be associated with increased risk for schizophrenia and major depressive disorder. This gene is present in an inter-alpha-trypsin inhibitor family gene cluster on chromosome 3.
Purification Method:
Affinity purification
Gene ID:
3699
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITIH3 Rabbit pAb (CAB9459) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
