The ITGB6 Polyclonal Antibody (CAB16904) is a valuable tool for researchers studying integrin beta 6 (ITGB6), a cell surface protein involved in cell adhesion and signaling processes. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blotting.ITGB6 is known to play a key role in regulating cell migration and invasion, particularly in the context of cancer progression. By targeting ITGB6 with this polyclonal antibody, researchers can effectively detect and analyze ITGB6 protein expression in different cell types, providing insights into its functions and potential therapeutic implications.
Further understanding of ITGB6 function is crucial for developing targeted therapies for cancer and other diseases where dysregulation of cell adhesion and migration processes contribute to pathology. The ITGB6 Polyclonal Antibody is a valuable tool for advancing research in this area and uncovering new opportunities for therapeutic intervention.
Product Name:
ITGB6 Rabbit Polyclonal Antibody
SKU:
CAB16904
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 732-788 of human ITGB6 (NP_000879.2).
centrosome, external side of plasma membrane, focal adhesion, nucleoplasm, plasma membrane
Calculated MW:
86kDa
Observed MW:
86kDa
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3694
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITGB6 Rabbit pAb (CAB16904) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
