ITGB3BP Rabbit Polyclonal Antibody (CAB14859)
- SKU:
- CAB14859
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | ITGB3BP Rabbit Polyclonal Antibody |
SKU: | CAB14859 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human ITGB3BP (NP_055103.3). |
Sequence: | MPVK RSLK LDGL LEEN SFDP SKIT RKKS VITY SPTT GTCQ MSLF ASPT SSEE QKHR NGLS NEKR KKLN HPSL TESK ESTT KDND EFMM LLSK VEKL SEEI MEIM QNLS SIQ |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | CENPR; NRIF3; TAP20; CENP-R; HSU37139; ITGB3BP |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Cytoplasm, Nucleus, centromere, kinetochore. |
Calculated MW: | 20kDa |
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23421 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |