ITGB1 Monoclonal Antibody [PAT47E2AT] (CPAB0681)
- SKU:
- CPAB0681
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT47E2AT
- Applications:
- WB
- ELISA
Description
ITGB1 Monoclonal Antibody [PAT47E2AT] (CPAB0681)
The ITGB1 Antibody (CPAB0681) is a high-quality research tool designed for investigating integrin beta-1 (ITGB1), a crucial cell surface receptor involved in cell adhesion and signaling. This polyclonal antibody is produced in rabbits and demonstrates high reactivity with human samples, making it suitable for a variety of research applications, including Western blotting and immunohistochemistry.Integrin beta-1 is known for its role in cell-extracellular matrix interactions, cell migration, and signal transduction pathways. Dysregulation of ITGB1 expression or function has been implicated in various diseases, including cancer, cardiovascular diseases, and inflammatory disorders.
Therefore, the ITGB1 Antibody is a valuable tool for studying the expression and localization of ITGB1 in different cell types and tissues, providing insights into its potential involvement in disease pathogenesis.By using the ITGB1 Antibody, researchers can gain a better understanding of the molecular mechanisms underlying ITGB1-mediated cellular processes and identify potential therapeutic targets for the treatment of ITGB1-related diseases. Its high specificity and sensitivity make it an essential tool for advancing research in cell biology, cancer biology, and therapeutic drug development.
Product Name: | ITGB1 Antibody |
Product Sku: | CPAB0681 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human ITGB1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ITGB1 protein 21-461 amino acids purified from Ecoli. |
Clone: | PAT47E2AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | ITGB1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Integrins are heterodimeric proteins consist of alpha and beta subunits. There are more than 18 alpha and 8 beta subunits discovered in mammals. Integrin family members are membrane receptors that participates in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 encodes a beta subunit. |
Synonyms: | Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12, Integrin beta 1, CD29, VLAB. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |