The ITGAD Polyclonal Antibody (PACO02135) is a valuable tool for researchers studying ITGAD, a cell surface integrin molecule involved in cell adhesion and migration. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in various applications, including Western blotting. By targeting the ITGAD protein, researchers can effectively detect and analyze its expression in different cell types, making it an ideal choice for studies in immunology and cancer research.
ITGAD, also known as integrin alpha D, is crucial for various cellular processes, including immune cell migration and adhesion to endothelial cells. Its role in mediating immune cell functions makes it a promising target for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions. By studying the function of ITGAD, researchers can gain valuable insights into potential therapeutic strategies that target immune cell activity in these disease contexts.
Antibody Name:
ITGAD Antibody
Antibody SKU:
PACO02135
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Integrin alphaD.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ITGAD; Integrin alpha-D; ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD11d
UniProt Protein Function:
ITGAD: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood- borne pathogens, particulate matter, and senescent erythrocytes from the blood. Belongs to the integrin alpha chain family.Protein type: Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 16p11.2Cellular Component: cell surface; plasma membrane; integrin complexMolecular Function: metal ion bindingBiological Process: integrin-mediated signaling pathway; heterotypic cell-cell adhesion; extracellular matrix organization and biogenesis; activated T cell proliferation; immune response
