The ITGA7 Polyclonal Antibody (CAB14246) is a valuable tool for research studies focused on integrin alpha 7 (ITGA7), a cell surface protein involved in cell adhesion and signaling processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been verified for use in Western blotting applications. By binding specifically to the ITGA7 protein, this antibody enables the accurate detection and analysis of ITGA7 expression in various cell types, making it particularly well-suited for investigations in the fields of cell biology and muscle physiology.ITGA7 plays a crucial role in mediating cell-matrix interactions and is known to be essential for muscle development and function.
Dysregulation of ITGA7 expression has been implicated in various diseases, including muscular dystrophy and cancer. Therefore, studying the function and regulation of ITGA7 is essential for gaining insights into these pathological conditions and potentially identifying novel therapeutic targets.Overall, the ITGA7 Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of ITGA7 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it an indispensable asset for studies aiming to elucidate the intricate mechanisms underlying ITGA7-mediated biological functions.
Product Name:
ITGA7 Rabbit Polyclonal Antibody
SKU:
CAB14246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 880-1020 of human ITGA7 (NP_002197.2).
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
3679
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using ITGA7 Rabbit pAb (CAB14246) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
