Integrin alpha 5 (ITGA5/CD49e) Rabbit Polyclonal Antibody (CAB6209)
- SKU:
- CAB6209
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Integrin alpha 5 (ITGA5/CD49e) Rabbit Polyclonal Antibody |
SKU: | CAB6209 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-1000 of human Integrin alpha 5 (ITGA5/CD49e) (NP_002196.4). |
Sequence: | TVPH LRDT KKTI QFDF QILS KNLN NSQS DVVS FRLS VEAQ AQVT LNGV SKPE AVLF PVSD WHPR DQPQ KEED LGPA VHHV YELI NQGP SSIS QGVL ELSC PQAL EGQQ LLYV TRVT GLNC TTNH PINP KGLE LDPE GSLH HQQK REAP SRSS ASSG PQIL KCPE AECF RLRC ELGP LHQQ ESQS LQLH FRVW AKTF LQRE HQPF SLQC EAVY KALK MPYR ILPR QLPQ KERQ VATA VQWT KAEG SYGV PLW |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | FNRA; CD49e; VLA-5; VLA5A; Integrin alpha 5 (ITGA5/CD49e) |
Positive Sample: | A-549,NIH/3T3,HT-1080,Rat heart,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 115kDa |
Observed MW: | 135kDa |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Purification Method: | Affinity purification |
Gene ID: | 3678 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |