The ITGA3 Polyclonal Antibody (CAB17502) is a valuable tool for researchers studying integrin alpha 3 (ITGA3), a cell adhesion molecule involved in various biological processes such as cell migration, proliferation, and differentiation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the ITGA3 protein, this antibody enables precise detection and analysis in different cell types, making it an essential resource for investigations in cell biology, cancer research, and tissue development.
ITGA3, a member of the integrin family, plays a crucial role in cell adhesion and signaling, making it a promising target for exploring cancer progression, tissue repair, and developmental processes. Its involvement in cell-matrix interactions and signal transduction pathways highlights its potential significance in various physiological and pathological conditions. Understanding the function of ITGA3 is essential for advancing our knowledge of cell behavior and designing novel therapeutic strategies targeting integrin-mediated processes.
Product Name:
ITGA3 Rabbit Polyclonal Antibody
SKU:
CAB17502
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 85-260 of human ITGA3 (P26006).
Cell membrane, Cell projection, Lipid-anchor, Single-pass type I membrane protein, filopodium membrane, invadopodium membrane.
Calculated MW:
117kDa
Observed MW:
125kDa/130kDa
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.
Purification Method:
Affinity purification
Gene ID:
3675
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITGA3 Rabbit pAb (CAB17502) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
