The Integrin Alpha 11 Polyclonal Antibody (CAB10084) is a valuable tool for researchers studying integrin alpha 11, a cell surface protein involved in cell adhesion and signaling processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By binding specifically to the integrin alpha 11 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology, tissue engineering, and cancer research.Integrin alpha 11 is known to play a crucial role in the regulation of cell behavior, including cell proliferation, migration, and differentiation.
Dysregulation of integrin alpha 11 expression has been associated with various diseases, such as fibrosis, cancer, and vascular disorders. Therefore, understanding the function and regulation of integrin alpha 11 is essential for developing therapeutic interventions targeting these conditions.Researchers interested in exploring the function of integrin alpha 11 in cellular processes or disease pathology will find the Integrin Alpha 11 Polyclonal Antibody (CAB10084) to be a valuable tool for their investigations. Its specificity, sensitivity, and reliability make it a trusted reagent for studying integrin alpha 11 biology across different experimental settings.
Product Name:
ITGA11 Rabbit Polyclonal Antibody
SKU:
CAB10084
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 940-1141 of human ITGA11 (NP_001004439.1).
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.
Purification Method:
Affinity purification
Gene ID:
22801
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ITGA11 antibody (CAB10084) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
