The ITGA10 Polyclonal Antibody (CAB16704) is a specialized antibody designed for research involving ITGA10, a cell surface integrin protein known for its role in cell adhesion and signaling. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it a valuable tool for studying ITGA10 expression and function.Integrins are essential for cell adhesion to the extracellular matrix and are involved in various physiological processes such as cell migration, proliferation, and differentiation. ITGA10, a member of the integrin alpha subunit family, is particularly important in mediating interactions between cells and the extracellular matrix in connective tissues.The ITGA10 Polyclonal Antibody enables researchers to detect and analyze ITGA10 protein levels in various cell types and tissues, providing valuable insights into its function and involvement in processes such as tissue development, wound healing, and fibrosis.
Its application in Western blotting and other techniques makes it a versatile tool for studies in cell biology, tissue engineering, and therapeutic development. Understanding the role of ITGA10 in health and disease is essential for uncovering potential therapeutic targets for conditions involving abnormal cell adhesion and tissue remodeling, making this antibody an invaluable resource for researchers in the fields of biomedicine and regenerative medicine.
Product Name:
ITGA10 Polyclonal Antibody
SKU:
CAB16704
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide of human ITGA10
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:100 - 1:500
Synonyms:
PRO827; ITGA10
Positive Sample:
HUVEC
Conjugate:
Unconjugated
Cellular Localization:
external side of plasma membrane, plasma membrane
Calculated MW:
128kDa
Observed MW:
128kDa
Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8515
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of HUVEC, using ITGA10 antibody (CAB16704) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.8s.
