The ISX Antibody (PAC027669) is a highly specific and sensitive tool for researchers studying the ISX protein, which has been implicated in various cellular functions, particularly in the regulation of gene expression. This polyclonal antibody, generated in rabbits, is well-suited for Western blot applications and has been validated for use with human samples.The ISX protein is known to play a crucial role in controlling transcriptional activity and has been linked to processes such as metabolism, development, and differentiation. By targeting the ISX protein, researchers can gain valuable insights into the molecular mechanisms underlying these biological processes.
With its high reactivity and specificity, the ISX Antibody is an excellent choice for studies in molecular biology, biochemistry, and cell biology. Its ability to detect and analyze the ISX protein in various cell types makes it a versatile tool for investigating the role of this protein in health and disease. Researchers studying gene regulation, metabolic pathways, and developmental processes will find the ISX Antibody to be an indispensable resource in their work.
Antibody Name:
ISX Antibody (PACO27669)
Antibody SKU:
PACO27669
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Intestine-specific homeobox protein (1-245AA)
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO27669 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human glioma using PACO27669 at dilution of 1:100.
Background:
Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine (By similarity).
ISX: Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCMO1 expression in the intestine.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 22q12.3Cellular Component: nucleusMolecular Function: sequence-specific DNA bindingBiological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the RAXLX homeobox gene family. [provided by RefSeq, Jul 2008]
