The IST1 Polyclonal Antibody (CAB9401) is a valuable tool for researchers studying IST1, a protein involved in cytokinesis and membrane trafficking processes. This antibody, developed using rabbit immunization, exhibits high specificity for IST1 in human samples and has been validated for use in Western blot applications. By binding to the IST1 protein, this antibody enables accurate detection and analysis of IST1 in various cell types, making it ideal for investigations in cell biology and molecular biology.IST1 is a key player in cell division and vesicle trafficking, making it a crucial target for research on cellular processes and organelle dynamics.
Understanding the function of IST1 can provide insights into mechanisms underlying cellular proliferation and membrane dynamics, with implications for studies on cancer, neurodegenerative diseases, and developmental biology. The IST1 Polyclonal Antibody offers a reliable tool for investigating the role of IST1 in cellular pathways and disease processes, advancing our understanding of fundamental biological processes.
Product Name:
IST1 Rabbit Polyclonal Antibody
SKU:
CAB9401
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human IST1 (NP_001257906.1).
This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
9798
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IST1 Rabbit pAb (CAB9401) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
