The ISOC1 Polyclonal Antibody (PAC053146) is a valuable tool for research involving ISOC1, a key protein involved in DNA repair and maintenance. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the ISOC1 protein, allowing for precise detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and genetics.ISOC1 is essential for maintaining genomic stability and preventing the accumulation of DNA damage, making it a crucial player in cell survival and proliferation.
Research on ISOC1 is important for understanding the mechanisms of DNA repair and the development of potential treatments for diseases related to DNA damage, such as cancer and genetic disorders. By elucidating the functions of ISOC1, researchers can uncover new insights into the molecular processes underlying these conditions and identify novel therapeutic targets for intervention.
Western Blot. Positive WB detected in: SH-SY5Y whole cell lysate. All lanes: ISOC1 antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 33 kDa. Observed band size: 33 kDa.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO53146 at dilution of 1:100.
Background:
cytoplasm, extracellular exosome, peroxisome
Synonyms:
Isochorismatase domain-containing protein 1, ISOC1
UniProt Protein Function:
ISOC1: Belongs to the isochorismatase family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 5q22.1-q33.3Cellular Component: cytoplasm; peroxisomeMolecular Function: protein binding