The ISM2 Polyclonal Antibody (PACO20682) is a valuable tool for researchers studying ISM2, a protein involved in immune regulation and inflammatory responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ISM2 protein, this antibody allows for the detection and analysis of ISM2 in various cell types, making it an essential reagent for studies in immunology and cancer research.ISM2 is known for its role in modulating immune responses and inflammation, making it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of ISM2 is crucial for the development of therapies that can manipulate immune responses in these disease contexts. With its high specificity and reliability, the ISM2 Polyclonal Antibody is a valuable tool for researchers investigating the role of ISM2 in immune regulation and disease.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20682(ISM2 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE,Lysate: 40 µg,Lane 1-3: 293T cells, LO2 cells, Lovo cells,Primary antibody: PACO20682(ISM2 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 5 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20682(ISM2 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The protein encoded by this gene contains a type 1 thrombospondin domain, which is present in thrombospondin, a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Synonyms:
isthmin 2
UniProt Protein Function:
THSD3: contains a type 1 thrombospondin domain, which is present in thrombospondin, a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Mar 2009]Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 14q24.3
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene contains a type 1 thrombospondin domain, which is present in thrombospondin, a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Mar 2009]
