Islet1 Rabbit Polyclonal Antibody (CAB6383)
- SKU:
- CAB6383
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | Islet1 Rabbit Polyclonal Antibody |
SKU: | CAB6383 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human Islet1 (NP_002193.2). |
Sequence: | MGDM GDPP KKKR LISL CVGC GNQI HDQY ILRV SPDL EWHA ACLK CAEC NQYL DESC TCFV RDGK TYCK RDYI RLYG IKCA KCSI GFSK NDFV MRAR SKVY HIEC FRCV ACSR QLIP GDEF ALRE DGLF CRAD HDVV ERAS LGAG DPLS PLHP ARPL QMAA EPIS ARQP ALRP HVHK QPEK TTRV RTVL NEKQ LHTL RTCY AANP RPDA LMKE QLVE MTGL SPRV IRVW FQNK RCKD KKRS IMMK QLQQ QQPN DKTN IQGM TGTP MVAA SPER HDGG LQAN PVEV QSYQ PPWK VLSD FALQ SDID QPAF QQLV NFSE GGPG SNST GSEV ASMS SQLP DTPN SMVA SPIE A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Isl-1; ISLET1; Islet1 |
Positive Sample: | HeLa,SH-SY5Y,Mouse thymus,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 50kDa |
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Purification Method: | Affinity purification |
Gene ID: | 3670 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |