The ISG15 Rabbit Monoclonal Antibody (CAB2416) is a valuable tool for research involving ISG15, a protein involved in the immune response and antiviral activity. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for Western blot applications. By binding to the ISG15 protein, this antibody enables precise detection and analysis in a variety of cell types, providing crucial insights for studies in immunology and virology.ISG15, an interferon-stimulated gene, plays a key role in the innate immune response by regulating various cellular processes such as antiviral immunity and inflammation. Its involvement in immune signaling pathways makes it a promising target for research into viral infections, autoimmune diseases, and inflammatory disorders.
Understanding the function of ISG15 is essential for developing new therapeutic strategies to combat these conditions.In summary, the ISG15 Rabbit Monoclonal Antibody (CAB2416) is a high-quality antibody that offers researchers a reliable tool for investigating the intricate mechanisms of immune response and antiviral defense mediated by the ISG15 protein. Its specificity and sensitivity make it a valuable asset for advancing our understanding of immune regulation and developing innovative treatments for infectious and inflammatory diseases.
Product Name:
ISG15 Rabbit Monoclonal Antibody
SKU:
CAB2416
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_005092.1).
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.
Purification Method:
Affinity purification
Gene ID:
9636
Clone Number:
ARC53794
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and ISG15 knockdown (KD) 293T cells, using [KD Validated] ISG15 Rabbit mAb (CAB2416) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
