ISCU Rabbit Polyclonal Antibody (CAB7082)
- SKU:
- CAB7082
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ISCU Rabbit Polyclonal Antibody |
SKU: | CAB7082 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human ISCU (NP_998760.1). |
Sequence: | MAAA GAFR LRRA ASAL LLRS PRLP AREL SAPA RLYH KKVV DHYE NPRN VGSL DKTS KNVG TGLV GAPA CGDV MKLQ IQVD EKGK IVDA RFKT FGCG SAIA SSSL ATEW VKGK TVEE ALTI KNTD IAKE LCLP PVKL HCSM LAED AIKA ALAD YKLK QEPK KGEA EKK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik; ISCU |
Positive Sample: | HT-1080,U-87MG,293T,A-549,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus. |
Calculated MW: | 18kDa |
Observed MW: | 14-18kDa |
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Purification Method: | Affinity purification |
Gene ID: | 23479 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |