UniProt Protein Function: | ISCA2: Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family.Chromosomal Location of Human Ortholog: 14q24.3Cellular Component: mitochondrial matrixMolecular Function: 2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; ferrous iron binding; protein binding; structural molecule activityBiological Process: iron-sulfur cluster assembly; sulfur metabolic processDisease: Multiple Mitochondrial Dysfunctions Syndrome 4 |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] |
UniProt Code: | Q86U28 |
NCBI GenInfo Identifier: | 432134254 |
NCBI Gene ID: | 122961 |
NCBI Accession: | NP_001258936.1 |
UniProt Secondary Accession: | Q86U28,Q8IYZ0, Q96BB2, A6NFF1, A8K3W3, G3V291 |
UniProt Related Accession: | Q86U28 |
Molecular Weight: | 6,211 Da |
NCBI Full Name: | iron-sulfur cluster assembly 2 homolog, mitochondrial isoform 2 |
NCBI Synonym Full Names: | iron-sulfur cluster assembly 2 |
NCBI Official Symbol: | ISCA2Â Â |
NCBI Official Synonym Symbols: | ISA2; HBLD1; MMDS4; c14_5557Â Â |
NCBI Protein Information: | iron-sulfur cluster assembly 2 homolog, mitochondrial |
UniProt Protein Name: | Iron-sulfur cluster assembly 2 homolog, mitochondrial |
UniProt Synonym Protein Names: | HESB-like domain-containing protein 1 |
Protein Family: | Iron-sulfur cluster assembly |
UniProt Gene Name: | ISCA2Â Â |
UniProt Entry Name: | ISCA2_HUMAN |