IRX1 Antibody (PACO05356)
- SKU:
- PACO05356
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
IRX1 Antibody (PACO05356)
The IRX1 Polyclonal Antibody (PACO05356) is a valuable tool for researchers studying the IRX1 protein, a transcription factor implicated in various cellular processes, including development and differentiation. This antibody, raised in rabbits, displays high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the IRX1 protein, researchers can analyze its expression and function in different cell types, making it a versatile tool for studies in developmental biology and cancer research.
IRX1 is known for its role in regulating gene expression and cellular growth, making it a potential target for investigating developmental disorders and cancer progression. By understanding the mechanisms underlying IRX1 function, researchers can gain insights into how abnormalities in its activity contribute to disease pathogenesis. This antibody is essential for unraveling the complex roles of IRX1 in various biological processes, paving the way for potential therapeutic interventions targeting this transcription factor.
| Antibody Name: | IRX1 Antibody (PACO05356) |
| Antibody SKU: | PACO05356 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the Internal region of human IRX1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | IRX1; IRXA1; Iroquois-class homeodomain protein IRX-1; Homeodomain protein IRXA1; Iroquois homeobox protein 1 |
| UniProt Protein Function: | IRX1: a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011] |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 5p15.3 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding Biological Process: regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011] |
| UniProt Code: | P78414 |
| NCBI GenInfo Identifier: | 51479177 |
| NCBI Gene ID: | 79192 |
| NCBI Accession: | NP_077313 |
| UniProt Related Accession: | P78414 |
| Molecular Weight: | 49kDa |
| NCBI Full Name: | iroquois-class homeodomain protein IRX-1 |
| NCBI Synonym Full Names: | iroquois homeobox 1 |
| NCBI Official Symbol: | IRX1Â Â |
| NCBI Official Synonym Symbols: | IRX-5; IRXA1Â Â |
| NCBI Protein Information: | iroquois-class homeodomain protein IRX-1 |
| UniProt Protein Name: | Iroquois-class homeodomain protein IRX-1 |
| UniProt Synonym Protein Names: | Homeodomain protein IRXA1; Iroquois homeobox protein 1 |
| Protein Family: | Iroquois-class homeodomain protein |
| UniProt Gene Name: | IRX1Â Â |
| UniProt Entry Name: | IRX1_HUMAN |
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