IRS2 Rabbit Polyclonal Antibody (CAB7945)
- SKU:
- CAB7945
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IRS2 Rabbit Polyclonal Antibody |
SKU: | CAB7945 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1238-1338 of human IRS2 (NP_003740.2). |
Sequence: | PMRR ETSA GFQN GLNY IAID VREE PGLP PQPQ PPPP PLPQ PGDK SSWG RTRS LGGL ISAV GVGS TGGG CGGP GPGA LPPA NTYA SIDF LSHH LKEA TIVK E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | IRS-2; IRS2 |
Positive Sample: | SH-SY5Y,U2OS |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cytosol. |
Calculated MW: | 137kDa |
Observed MW: | 180kDa |
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Purification Method: | Affinity purification |
Gene ID: | 8660 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |