The IRF9 Polyclonal Antibody is specifically designed for research involving the IRF9 protein, a key transcription factor involved in regulating immune responses. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.IRF9, also known as interferon regulatory factor 9, plays a critical role in mediating the antiviral and immune response by forming transcription complexes with other proteins. Its involvement in the regulation of interferon-stimulated genes makes it a crucial player in the immune system's defense against viruses and pathogens.
Researchers studying viral infections, autoimmune diseases, and immune system disorders will find the IRF9 Polyclonal Antibody invaluable for detecting and analyzing IRF9 protein expression in various cell types. This antibody enables researchers to gain insights into the molecular mechanisms underlying immune responses, paving the way for the development of novel therapeutic strategies targeting IRF9 in the treatment of immune-related diseases.
Product Name:
IRF9 Polyclonal Antibody
SKU:
CAB21331
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 113-255 of human IRF9 (NP_006075.3).
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Mutations in this gene result in Immunodeficiency 65.
Purification Method:
Affinity purification
Gene ID:
10379
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IRF9 antibody (CAB21331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
