IRF8 Rabbit Polyclonal Antibody (CAB13677)
- SKU:
- CAB13677
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | IRF8 Rabbit Polyclonal Antibody |
SKU: | CAB13677 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP_002154.1). |
Sequence: | ECGR SEID ELIK EPSV DDYM GMIK RSPS PPEA CRSQ LLPD WWAQ QPST GVPL VTGY TTYD AHHS AFSQ MVIS FYYG GKLV GQAT TTCP EGCR LSLS QPGL PGTK LYGP EGLE LVRF PPAD AIPS ERQR QVTR KLFG HLER GVLL HSSR QGVF VKRL CQGR VFCS GNAV VCKG RPNK LERD EVVQ VFDT SQFF RELQ QFYN SQGR LPDG RVVL CFGE EFPD MAPL RSKL ILVQ IEQL YVRQ LAEE AGKS CGAG SVMQ APEE PPPD QVFR MFPD ICAS HQRS FFRE NQQI TV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP; IRF8 |
Positive Sample: | HL-60 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 48kDa |
Observed MW: | 50kDa |
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Purification Method: | Affinity purification |
Gene ID: | 3394 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |