The IRF7 Polyclonal Antibody (CAB0159) is a valuable tool for researchers studying the IRF7 protein, a key transcription factor involved in the regulation of immune responses. This antibody, raised in rabbits, is highly specific to human IRF7 and has been validated for use in Western blot applications. By binding to the IRF7 protein, this antibody enables the detection and analysis of IRF7 expression in various cell types, making it ideal for investigations in immunology and infectious disease research.IRF7 is a crucial mediator of the innate immune response, playing a vital role in the activation of type I interferon genes in response to viral infections.
Dysregulation of IRF7 has been linked to autoimmune diseases, viral infections, and cancer, making it a target of interest for therapeutic development. By studying the function and regulation of IRF7, researchers can gain insights into immune responses and potentially identify novel strategies for treating immune-related disorders.Overall, the IRF7 Polyclonal Antibody (CAB0159) is a reliable tool for investigating the role of IRF7 in immune regulation and disease pathogenesis, offering valuable insights for advancing our understanding of immune responses and potentially identifying new targets for therapeutic intervention.
Product Name:
IRF7 Rabbit Polyclonal Antibody
SKU:
CAB0159
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IRF7 (NP_001563.2).
This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses.
Purification Method:
Affinity purification
Gene ID:
3665
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse liver, using IRF7 antibody (CAB0159) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
