null

Irf5 Antibody (PACO27661)

SKU:
PACO27661
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Irf5 Antibody (PACO27661)

The IRF5 Polyclonal Antibody (PACO27661) is a valuable tool for researchers studying IRF5, a key transcription factor involved in the regulation of immune responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the IRF5 protein, this antibody enables the detection and analysis of IRF5 expression in a variety of cell types, making it well-suited for investigations in immunology and inflammatory diseases.

IRF5 is a critical regulator of immune responses, playing a crucial role in the activation of inflammatory pathways and the production of pro-inflammatory cytokines. Dysregulation of IRF5 has been implicated in a variety of autoimmune disorders and inflammatory conditions, highlighting its potential as a therapeutic target. By studying the function of IRF5, researchers can gain insights into the underlying mechanisms of these diseases and develop novel treatment strategies to modulate immune responses.

Antibody Name:Irf5 Antibody (PACO27661)
Antibody SKU:PACO27661
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Mouse
Immunogen:Recombinant Mouse Interferon regulatory factor 5 protein (1-497AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling.
Synonyms:Interferon regulatory factor 5 (IRF-5), Irf5
UniProt Protein Function:IRF5: Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling. Homodimer, when phosphorylated. Belongs to the IRF family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:DNA-binding; Transcription factor

Cellular Component: cytoplasm; nucleus

Molecular Function:DNA binding; protein binding; transcription factor activity

Biological Process: cytokine and chemokine mediated signaling pathway; defense response to virus; immune system process; innate immune response; positive regulation of apoptosis; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to muramyl dipeptide; response to peptidoglycan; transcription, DNA-dependent

UniProt Code:P56477
NCBI GenInfo Identifier:356991180
NCBI Gene ID:27056
NCBI Accession:NP_001239311.1
UniProt Related Accession:P56477
Molecular Weight:72 kDa
NCBI Full Name:interferon regulatory factor 5 isoform 1
NCBI Synonym Full Names:interferon regulatory factor 5
NCBI Official Symbol:Irf5  
NCBI Official Synonym Symbols:mirf5; AW491843  
NCBI Protein Information:interferon regulatory factor 5
UniProt Protein Name:Interferon regulatory factor 5
Protein Family:Interferon regulatory factor
UniProt Gene Name:Irf5  
UniProt Entry Name:IRF5_MOUSE

Related Products