IRF5 Monoclonal Antibody [P10T1AT] (CPAB0069)
- SKU:
- CPAB0069
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- P10T1AT
- Applications:
- WB
- ELISA
Description
IRF5 Monoclonal Antibody [P10T1AT] (CPAB0069)
The IRF5 Polyclonal Antibody (CPAB0069) is an essential tool for researchers studying the transcription factor IRF5, which plays a key role in the immune response and inflammatory processes. This antibody, produced in rabbits, has high specificity and sensitivity for human samples, making it reliable for use in Western blot applications. By targeting the IRF5 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.
IRF5 is known for its involvement in the regulation of immune responses, especially in the production of proinflammatory cytokines and type I interferons. Dysregulation of IRF5 has been linked to various autoimmune diseases, including lupus and rheumatoid arthritis, as well as certain types of cancer. By studying the role of IRF5, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop targeted therapies to modulate immune function and inflammation.
Product Name: | IRF5 Antibody |
Product Sku: | CPAB0069 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human IRF5 mAb, is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human IRF5 amino acids 176-24 purified from Ecoli. |
Clone: | P10T1AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | IRF5 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | IRF5 belongs to the interferon regulatory factor (IRF) family, which is a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. |
Synonyms: | Interferon regulatory factor 5, IRF-5, IRF5, SLEB10. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |