IRF4 Rabbit Polyclonal Antibody (CAB1052)
- SKU:
- CAB1052
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IRF4 Rabbit Polyclonal Antibody |
SKU: | CAB1052 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-451 of human IRF4 (NP_002451.2). |
Sequence: | DYVP DQPH PEIP YQCP MTFG PRGH HWQG PACE NGCQ VTGT FYAC APPE SQAP GVPT EPSI RSAE ALAF SDCR LHIC LYYR EILV KELT TSSP EGCR ISHG HTYD ASNL DQVL FPYP EDNG QRKN IEKL LSHL ERGV VLWM APDG LYAK RLCQ SRIY WDGP LALC NDRP NKLE RDQT CKLF DTQQ FLSE LQAF AHHG RSLP RFQV TLCF GEEF PDPQ RQRK LITA HVEP LLAR QLYY FAQQ NSGH FLRG YDLP EHIS NPED YHRS IRHS SIQE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MUM1; LSIRF; SHEP8; NF-EM5; IRF4 |
Positive Sample: | K-562,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3662 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |