IRF4 Rabbit Polyclonal Antibody (CAB0524)
- SKU:
- CAB0524
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IRF4 Rabbit Polyclonal Antibody |
SKU: | CAB0524 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-350 of human IRF4 (NP_002451.2). |
Sequence: | HPYT MTTP YPSL PAQQ VHNY MMPP LDRS WRDY VPDQ PHPE IPYQ CPMT FGPR GHHW QGPA CENG CQVT GTFY ACAP PESQ APGV PTEP SIRS AEAL AFSD CRLH ICLY YREI LVKE LTTS SPEG CRIS HGHT YDAS NLDQ VLFP YPED NGQR KNIE KLLS HLER GVVL WMAP DGLY AKRL CQSR IYWD GPLA LCND RPNK L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MUM1; LSIRF; SHEP8; NF-EM5; IRF4 |
Positive Sample: | THP-1,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 52kDa |
Observed MW: | 55kDa |
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3662 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |