IRF4 Monoclonal Antibody (CAB23227)
- SKU:
- CAB23227
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Frequently bought together:
Description
Product Name: | IRF4 Monoclonal Antibody |
SKU: | CAB23227 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 351-451 of human IRF4 (NP_001182215.1). |
Sequence: | ERDQ TCKL FDTQ QFLS ELQA FAHH GRSL PRFQ VTLC FGEE FPDP QRQR KLIT AHVE PLLA RQLY YFAQ QNSG HFLR GYDL PEHI SNPE DYHR SIRH SSIQ E |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | MUM1; LSIRF; SHEP8; NF-EM5; IRF4 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 52kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3662 |
Clone Number: | ARC58086 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |