The IRF2 Rabbit Monoclonal Antibody (CAB4843) is a highly specific antibody designed for research involving interferon regulatory factor 2 (IRF2), a transcription factor involved in the regulation of immune responses and cell growth. This monoclonal antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blotting.IRF2 plays a crucial role in the modulation of immune responses and has been implicated in various diseases, including cancer and autoimmune disorders.
By targeting IRF2, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially uncover new therapeutic targets for intervention.With its high specificity and sensitivity, the IRF2 Rabbit Monoclonal Antibody (CAB4843) is an invaluable tool for studying the role of IRF2 in immunology and cancer research. Its ability to detect and analyze IRF2 protein expression in different cell types makes it an essential reagent for investigating the intricate pathways involved in immune regulation and disease development.
Product Name:
IRF2 Rabbit Monoclonal Antibody
SKU:
CAB4843
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-349 of human IRF2 (P14316).
WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
IRF-2; IRF2
Positive Sample:
HeLa
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
39kDa
Observed MW:
50kDa
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Purification Method:
Affinity purification
Gene ID:
3660
Clone Number:
ARC0265
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using IRF2 Rabbit mAb (CAB4843) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
