IRAK4 Rabbit Polyclonal Antibody (CAB6208)
- SKU:
- CAB6208
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | IRAK4 Rabbit Polyclonal Antibody |
SKU: | CAB6208 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human IRAK4 (NP_057207.2). |
Sequence: | MNKP ITPS TYVR CLNV GLIR KLSD FIDP QEGW KKLA VAIK KPSG DDRY NQFH IRRF EALL QTGK SPTS ELLF DWGT TNCT VGDL VDLL IQNE FFAP ASLL LPDA VPKT ANTL PSKE AITV QQKQ MPFC DKDR TLMT PVQN LEQS YMPP DSSS PENK SLEV SDTR FHSF SFYE LKNV TNNF DERP ISVG GNKM GEGG FGVV YKGY VNNT TVAV KKLA AMVD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | IPD1; IMD67; REN64; IRAK-4; NY-REN-64; IRAK4 |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 52kDa |
Observed MW: | 55kDa |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51135 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |