The IRAK3 Polyclonal Antibody (CAB13402) is a valuable tool for researchers studying the IRAK3 protein, an essential component of the immune response pathway. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to IRAK3, this antibody enables accurate detection and analysis of the protein in a variety of cell types.IRAK3, also known as interleukin-1 receptor-associated kinase 3, plays a key role in regulating the immune response and inflammatory signaling pathways. Dysregulation of IRAK3 has been linked to various immune-related disorders, making it a promising target for therapeutic interventions.
Studying the function and expression of IRAK3 can provide valuable insights into the development of treatments for conditions such as autoimmune diseases, infections, and inflammatory disorders.With its specificity and reliability, the IRAK3 Polyclonal Antibody (CAB13402) is an essential tool for researchers seeking to explore the intricate mechanisms of immune regulation and inflammatory responses. Its applications in immunology and disease research make it a versatile asset for advancing our understanding of the immune system and developing targeted therapies.
Product Name:
IRAK3 Rabbit Polyclonal Antibody
SKU:
CAB13402
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 367-596 of human IRAK3 (NP_009130.2).
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
11213
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IRAK3 Rabbit pAb (CAB13402) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
