The IRAK2 Rabbit Monoclonal Antibody (CAB4655) is a powerful tool for researchers studying IRAK2, a key player in the innate immune response. This antibody, produced in rabbits, is highly specific for IRAK2 and has been validated for use in various applications such as Western blotting and immunohistochemistry.IRAK2, also known as interleukin-1 receptor-associated kinase 2, is a crucial mediator of Toll-like receptor and interleukin-1 receptor signaling pathways, leading to the activation of NF-κB and inflammatory responses. Dysregulation of IRAK2 has been implicated in various inflammatory diseases, making it a promising target for therapeutic intervention.
By using the IRAK2 Rabbit Monoclonal Antibody, researchers can detect and analyze IRAK2 expression in different cell types and tissues, providing valuable insights into its role in immune response regulation. This antibody is a valuable tool for studies in immunology, inflammation, and infectious diseases, ultimately contributing to the development of novel therapeutic strategies targeting IRAK2.
Product Name:
IRAK2 Rabbit Monoclonal Antibody
SKU:
CAB4655
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-250 of human IRAK2 (O43187).
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Purification Method:
Affinity purification
Gene ID:
3656
Clone Number:
ARC1078
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using IRAK2 Rabbit mAb (CAB4655) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
