The IRAK2 Polyclonal Antibody (CAB6635) is a valuable tool for researchers studying the IRAK2 protein, a key player in the Toll-like receptor signaling pathway involved in immune response. This antibody, generated in rabbits, is highly specific to human IRAK2 samples and has been validated for use in Western blot applications.IRAK2, a member of the interleukin-1 receptor-associated kinase (IRAK) family, plays a crucial role in the activation of inflammatory responses and the regulation of immune signaling. Dysregulation of IRAK2 has been implicated in various diseases, including autoimmune disorders, inflammation, and cancer.
By targeting this protein, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially develop new therapeutic strategies.With its high reactivity and specificity, the IRAK2 Polyclonal Antibody is an essential tool for investigating the function and regulation of IRAK2 in different cell types and disease contexts. Its versatility and reliability make it an ideal choice for studies in immunology, oncology, and other areas of biomedical research.
Product Name:
IRAK2 Rabbit Polyclonal Antibody
SKU:
CAB6635
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human IRAK2 (NP_001561.3).
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Purification Method:
Affinity purification
Gene ID:
3656
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IRAK2 antibody (CAB6635) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
