The IRAK1 Rabbit Monoclonal Antibody (CAB4439) is a valuable tool for researchers studying the interleukin-1 receptor-associated kinase 1 (IRAK1) protein, which plays a key role in the immune response and inflammation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting IRAK1 in human samples, making it suitable for use in Western blot applications.IRAK1 is a crucial component of the toll-like receptor (TLR) signaling pathway, involved in the activation of immune responses to pathogens. Dysregulation of IRAK1 has been implicated in various inflammatory disorders and autoimmune diseases, making it an attractive target for drug development and therapeutic interventions.
By using the IRAK1 Rabbit Monoclonal Antibody, researchers can gain insights into the function and regulation of IRAK1 in various cell types and disease contexts. This antibody enables the precise detection and quantification of IRAK1 levels, facilitating studies in immunology, inflammation, and infectious diseases. Its high specificity and reproducibility make it an essential tool for advancing our understanding of IRAK1 biology and its potential as a therapeutic target.
Product Name:
IRAK1 Rabbit Monoclonal Antibody
SKU:
CAB4439
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 215-499 of human IRAK1 (P51617).
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3654
Clone Number:
ARC1009
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using IRAK1 Rabbit mAb (CAB4439) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
