The IRAK1 Polyclonal Antibody (CAB12624) is a valuable tool for researchers studying IRAK1, a key protein involved in the regulation of immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the IRAK1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in immunology and inflammatory diseases.IRAK1, also known as Interleukin-1 receptor-associated kinase 1, plays a critical role in the activation of the innate immune system and the inflammatory response.
Dysregulation of IRAK1 has been implicated in various diseases, including autoimmune disorders, cancer, and inflammatory conditions. By investigating the function of IRAK1, researchers can gain insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets for intervention.Overall, the IRAK1 Polyclonal Antibody (CAB12624) is a valuable tool for researchers seeking to unravel the complex role of IRAK1 in immune regulation and inflammatory pathways, with potential implications for the development of novel treatment strategies.
Product Name:
IRAK1 Rabbit Polyclonal Antibody
SKU:
CAB12624
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 424-633 of human IRAK1 (NP_001020414.1).
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3654
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of 293T, using IRAK1 Rabbit pAb (CAB12624) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
